4 Comments
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Linh Tran's avatar

Really enjoyed this breakdown, had no idea that thalidomide ended up being repurposed!

Adele Lopes's avatar

Thank you Linh! Yeah it’s pretty cool! I actually wrote a startup that just went public called Biossil that’s using AI to repurpose drugs that are already designed and tested clinically that didn’t reach endpoints. There are some pretty interesting stories about repurposing there if you want to check the article and the company out.

John Charles Harman's avatar

Interesting. AI should change that fairly quickly.

Adele Lopes's avatar

Thank for the comment John! I actually have a post up about how AI is changing clinical trials and drug discovery here: https://adelelopes.substack.com/p/heres-to-the-last-failed-drug. No AI-designed drug has passed through all stages of clinical trials yet but things do look promising for the design and repurposing of drugs!